rad proteins

rad proteins
(= rad 50, 51, 52, 54, 55, 57, 59; MRE11, XRS2)
Yeast proteins coded by genes originally identified as being particularly sensitive to X-rays. Required for spontaneous and induced mitotic recombination, meiotic recombination and mating-type switching. Human homologues of many of these proteins have been identified. rad51 (37 kD) is the functional homologue of recA and promotes ATP-dependent homologous pairing and DNA strand exchange; binds Rad52.

Dictionary of molecular biology. 2004.

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